BRAIN METASTASES FROM BREAST CANCER HISTOLOGICALLY EXHIBIT SOLID GROWTH PATTERN WITH AT LEAST FOCAL COMEDONECROSIS: A HISTOPATHOLOGIC STUDY ON A MONOCENTRIC SERIES OF 30 CASES

Brain Metastases from Breast Cancer Histologically Exhibit Solid Growth Pattern with at Least Focal Comedonecrosis: A Histopathologic Study on a Monocentric Series of 30 Cases

Since there are no morphological clues capable of making a Moisturisers pathologist suspect a possible mammary origin of a metastatic lesion without adequate clinical information, the histologic diagnosis of brain metastasis from BC is still based on the immunohistochemical expression of mammary gland markers such as GATA-3, ERs, PgRs and HER-2.The

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Investigating spillover of multidrug-resistant tuberculosis from a prison: a spatial and molecular epidemiological analysis

Abstract Background Congregate settings may serve as institutional amplifiers of tuberculosis (TB) and multidrug-resistant tuberculosis (MDR-TB).We analyze spatial, epidemiological, and pathogen genetic data prospectively collected from neighborhoods Leather Coasters surrounding a prison in Lima, Peru, where inmates experience a high risk of MDR-TB

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Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway

Quinones can modify biological molecules through both redox-cycling reactions that yield radicals (semiquinone, superoxide and hydroxyl) and via covalent adduction to nucleophiles (e.g.thiols and amines).Kinetic data indicate that Cys residues in GSH and proteins are major targets.In the studies reported here, the interactions of a prototypic quino

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Development of the Optics Valley Photon suspended monorail train

Suspended monorail trains represent an important component of urban rail transit and this mode of transportation is regarded as promising for BC426 applications in China.This paper begins with an introductory interview of the development of suspended monorail trains and subsequently analyzes the technical schemes of the Optics Valley Photon suspend

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